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human pancreatic primary islets  (Prodo Labs)

 
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    Prodo Labs human pancreatic primary islets
    Human Pancreatic Primary Islets, supplied by Prodo Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pancreatic+islets/human+islets+primary/bio_rxiv__64898__2026__05__01__722128-37-0-10
    Average 86 stars, based on 1 article reviews
    human pancreatic primary islets - by Bioz Stars, 2026-10
    86/100 stars

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    Related Articles

    other:

    Article Title: Effects of Multiple Stressors on Pancreatic Human Islets Proteome Reveal New Insights into the Pathways Involved
    Article Snippet: Pancreatic islets were purchased from Prodo Labs ( https://prodolabs.com/ ).

    Article Title: Effects of multiple stressors on pancreatic human islets proteome reveal new insights into the pathways involved.
    Article Snippet: Pancreatic islets were purchased from Prodo Labs (https://prodolabs. com/).

    Article Title: Amyloid Precursor Protein in Pancreatic Islets
    Article Snippet: Isolated pancreatic islets were obtained from Prodo Labs (Aliso Viejo, CA, USA).

    Suspension:

    Article Title: Bioprinting of human primary and iPSC-derived islets with retained and comparable functionality.
    Article Snippet: .. Human cadaveric pancreatic islets were procured from Prodo Labs (San Francisco, USA) and maintained in suspension using the proprietary Prodo islet media for recovery (PIM(R)) with media changes every 2–3 d, which maintains a fasting islet state at 5 × 10−3 m glucose. ..

    Article Title: Stress-free Bioprinting of Human Primary and iPSC-derived Islets with Retained Functionality
    Article Snippet: .. Human cadaveric pancreatic islets were procured from Prodo Labs (San Francisco, USA) and maintained in suspension using the proprietary Prodo islet media for recovery (PIM(R)) with media changes every 2-3 days, which maintains a fasting islet state at 5 × 10 −3 M glucose. ..

    Purification:

    Article Title: Single-cell transcriptomics from human pancreatic islets: sample preparation matters
    Article Snippet: .. Origin and processing of pancreatic islets Purified human pancreatic islets were obtained from Prodo Laboratories (Aliso Viejo, CA) and were isolated from cadaverous donors whose organs were consented for research. ..

    Isolation:

    Article Title: Single-cell transcriptomics from human pancreatic islets: sample preparation matters
    Article Snippet: .. Origin and processing of pancreatic islets Purified human pancreatic islets were obtained from Prodo Laboratories (Aliso Viejo, CA) and were isolated from cadaverous donors whose organs were consented for research. ..



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    Evaluation of HLA mismatch impact on co-culture sensitivity and background activation. (A) Liver spheroid co-cultures comparing autologous and allogeneic (HLA-A*02 matched) effector donors. Data are presented as mean ± SD as shaded area of technical replicates (n=3) from 3 representative donor pairs (N = 3) for each HLA-A*02 background. Statistical significance relative of the autologous cultures compared to corresponding allogenic cultures two-way ANOVA with Tukey’s post-hoc test, p values are indicated for the overall comparison between autologous versus allogeneic data. (B) <t>Pancreatic</t> islet spheroid co-cultures comparing HLA-matched (4/6 alleles) and HLA-mismatched conditions. Data illustrate the increased signal-to-noise ratio in HLA-matched systems compared to the elevated background activation observed in allogeneic co-cultures. Data are presented as mean of N = 5 donors for the matched dataset and N = 4 donors for the unmatched dataset run in technical replicates (n=2).
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    Evaluation of HLA mismatch impact on co-culture sensitivity and background activation. (A) Liver spheroid co-cultures comparing autologous and allogeneic (HLA-A*02 matched) effector donors. Data are presented as mean ± SD as shaded area of technical replicates (n=3) from 3 representative donor pairs (N = 3) for each HLA-A*02 background. Statistical significance relative of the autologous cultures compared to corresponding allogenic cultures two-way ANOVA with Tukey’s post-hoc test, p values are indicated for the overall comparison between autologous versus allogeneic data. (B) <t>Pancreatic</t> islet spheroid co-cultures comparing HLA-matched (4/6 alleles) and HLA-mismatched conditions. Data illustrate the increased signal-to-noise ratio in HLA-matched systems compared to the elevated background activation observed in allogeneic co-cultures. Data are presented as mean of N = 5 donors for the matched dataset and N = 4 donors for the unmatched dataset run in technical replicates (n=2).
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    Evaluation of HLA mismatch impact on co-culture sensitivity and background activation. (A) Liver spheroid co-cultures comparing autologous and allogeneic (HLA-A*02 matched) effector donors. Data are presented as mean ± SD as shaded area of technical replicates (n=3) from 3 representative donor pairs (N = 3) for each HLA-A*02 background. Statistical significance relative of the autologous cultures compared to corresponding allogenic cultures two-way ANOVA with Tukey’s post-hoc test, p values are indicated for the overall comparison between autologous versus allogeneic data. (B) <t>Pancreatic</t> islet spheroid co-cultures comparing HLA-matched (4/6 alleles) and HLA-mismatched conditions. Data illustrate the increased signal-to-noise ratio in HLA-matched systems compared to the elevated background activation observed in allogeneic co-cultures. Data are presented as mean of N = 5 donors for the matched dataset and N = 4 donors for the unmatched dataset run in technical replicates (n=2).
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    Image Search Results


    Evaluation of HLA mismatch impact on co-culture sensitivity and background activation. (A) Liver spheroid co-cultures comparing autologous and allogeneic (HLA-A*02 matched) effector donors. Data are presented as mean ± SD as shaded area of technical replicates (n=3) from 3 representative donor pairs (N = 3) for each HLA-A*02 background. Statistical significance relative of the autologous cultures compared to corresponding allogenic cultures two-way ANOVA with Tukey’s post-hoc test, p values are indicated for the overall comparison between autologous versus allogeneic data. (B) Pancreatic islet spheroid co-cultures comparing HLA-matched (4/6 alleles) and HLA-mismatched conditions. Data illustrate the increased signal-to-noise ratio in HLA-matched systems compared to the elevated background activation observed in allogeneic co-cultures. Data are presented as mean of N = 5 donors for the matched dataset and N = 4 donors for the unmatched dataset run in technical replicates (n=2).

    Journal: Frontiers in Immunology

    Article Title: Translational strategy to support the first-in-human study of a TCR-like T cell bispecific with an in vitro -based safety approach

    doi: 10.3389/fimmu.2026.1736584

    Figure Lengend Snippet: Evaluation of HLA mismatch impact on co-culture sensitivity and background activation. (A) Liver spheroid co-cultures comparing autologous and allogeneic (HLA-A*02 matched) effector donors. Data are presented as mean ± SD as shaded area of technical replicates (n=3) from 3 representative donor pairs (N = 3) for each HLA-A*02 background. Statistical significance relative of the autologous cultures compared to corresponding allogenic cultures two-way ANOVA with Tukey’s post-hoc test, p values are indicated for the overall comparison between autologous versus allogeneic data. (B) Pancreatic islet spheroid co-cultures comparing HLA-matched (4/6 alleles) and HLA-mismatched conditions. Data illustrate the increased signal-to-noise ratio in HLA-matched systems compared to the elevated background activation observed in allogeneic co-cultures. Data are presented as mean of N = 5 donors for the matched dataset and N = 4 donors for the unmatched dataset run in technical replicates (n=2).

    Article Snippet: Pancreatic Islets: 3D InSight Islet Microtissues (Cat: MT-04-002-01-60, InSphero) composed of primary alpha, beta, and delta cells were used.

    Techniques: Co-Culture Assay, Activation Assay, Comparison